Carina C. Kern

The paper shows that in C. elegans, lifespan is limited by competing senescent pathologies, and removing one can unmask another, indicating lifespan extension may not reflect reduced aging rate.

The paper uses machine learning to predict lifespan and causes of death in aging C. elegans by analyzing senescent pathology and genetic factors.

The paper shows that C. elegans hermaphrodites undergo reproductive death after reproduction, which is suppressed by germline removal and linked to lifespan extension.

This study shows that C. elegans mothers transfer yolk to offspring via lactation, a process promoted by insulin/IGF-1 signalling, leading to reproductive death.