Ramón García‐Escudero

The paper identifies functionally distinct and pharmacologically targetable cancer-associated fibroblast (CAF) programs in head and neck cancer using proteomic and functional assays.

This study identifies GRK2's role in hair follicle homeostasis by showing its deletion leads to cyst formation, stem cell disruption, and hair loss in mice.

This paper introduces a non-viral CRISPR/Cas9 method using cationic polymers to generate mouse lung cancer models by inactivating tumor suppressor genes, enabling rapid and flexible hypothesis testing.

This study detects cancer gene mutations in saliva and plasma of Fanconi anemia patients to predict oral cancer and precursor lesions, finding that mutations correlate with disease development.

The paper identifies HD-specific mis-splicing using intersect-RNA-seq in human and mouse models, revealing pathogenic splicing factors and effector genes.

The paper clusters head and neck squamous cell carcinomas based on lncRNA expression and identifies molecular and clinical associations.