Author

Caridad Miró-Pina

Centre National de la Recherche ScientifiqueORCID 0000-0001-5654-8073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Olivier ArnaiziD· 3 shared Sandra DuharcourtiD· 3 shared Adeline Humbert· 2 shared Andrea FrapportiiD· 2 shared Augustin de Vanssay· 2 shared Olivia CharmantiD· 2 shared Alexey A. PotekhiniD· 1 shared Amandine TouzeauiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersGenomics

Olivier ArnaizORCID

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3 papers

Recent·Most cited

The tiny germline chromosomes of Paramecium aurelia have anexceptionally high recombination rate and are capped by a new class of Helitrons

Olivier Arnaiz, Frédéric Guèrin, Arnaud Couloux, Caridad Miró-Pina, Guillaume Pellerin, Irina Nekrasova, Joëlle Amselem, Jean‐Marc Aury, Simran Bhullar, Andrea Frapporti, Emmanuelle Lerat, Isabelle Luyten, Sophie Malinsky, Nathalie Mathy, Alexey A. Potekhin, , Linda Sperling

The paper reports the genome of Paramecium aurelia, revealing tiny germline chromosomes with an exceptionally high recombination rate and a new class of Helitrons at their ends.

BMC Biology · Apr 16, 2026Peer-reviewedGenomics

A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium

Caridad Miró-Pina, Olivia Charmant, Marina Giovannetti, Augustin de Vanssay, Andrea Frapporti, Adeline Humbert, Maoussi Lhuillier‐Akakpo, Guillaume Chevreux, Olivier Arnaiz, Sandra Duharcourt

The paper shows PRC2 controls small RNA dynamics during DNA elimination in Paramecium by selectively degrading non-TE scnRNAs, independent of its histone methyltransferase activity.

Nucleic Acids Research · Sep 27, 2025Peer-reviewedGenomics

Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements

Caridad Miró-Pina, Takayuki Kawaguchi, Olivia Charmant, Audrey Michaud, Isadora S. Cohen, Adeline Humbert, Yan Jaszczyszyn, Laurence Del Maestro, Daniel Holoch, Slimane Ait‐Si‐Ali, Olivier Arnaiz, Raphaël Margueron, Sandra Duharcourt

The paper identifies PRC2 cofactors that mediate small RNA recruitment to repress transposable elements in Paramecium.

bioRxiv · Aug 12, 2021 · PreprintMolecular Biology