Author

Andrea Frapporti

Centre National de la Recherche ScientifiqueORCID 0000-0002-4973-596XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Augustin de Vanssay· 2 shared Caridad Miró-PinaiD· 2 shared Olivier ArnaiziD· 2 shared Sandra DuharcourtiD· 2 shared Adeline Humbert· 1 shared Alex Appert· 1 shared Alexey A. PotekhiniD· 1 shared Amandine TouzeauiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersGenomics

Augustin de Vanssay

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3 papers

Recent·Most cited

The tiny germline chromosomes of Paramecium aurelia have anexceptionally high recombination rate and are capped by a new class of Helitrons

Olivier Arnaiz, Frédéric Guèrin, Arnaud Couloux, Caridad Miró-Pina, Guillaume Pellerin, Irina Nekrasova, Joëlle Amselem, Jean‐Marc Aury, Simran Bhullar, Andrea Frapporti, Emmanuelle Lerat, Isabelle Luyten, Sophie Malinsky, Nathalie Mathy, Alexey A. Potekhin, , Linda Sperling

The paper reports the genome of Paramecium aurelia, revealing tiny germline chromosomes with an exceptionally high recombination rate and a new class of Helitrons at their ends.

BMC Biology · Apr 16, 2026Peer-reviewedGenomics

A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium

Caridad Miró-Pina, Olivia Charmant, Marina Giovannetti, Augustin de Vanssay, Andrea Frapporti, Adeline Humbert, Maoussi Lhuillier‐Akakpo, Guillaume Chevreux, Olivier Arnaiz, Sandra Duharcourt

The paper shows PRC2 controls small RNA dynamics during DNA elimination in Paramecium by selectively degrading non-TE scnRNAs, independent of its histone methyltransferase activity.

Nucleic Acids Research · Sep 27, 2025Peer-reviewedGenomics

DREAM represses distinct targets by cooperating with different THAP domain proteins

Csenge Gal, Francesco Nicola Carelli, Alex Appert, Chiara Cerrato, Ni Huang, Dong Yan, Jane Murphy, Andrea Frapporti, Julie Ahringer

The paper shows that DREAM complex represses distinct gene targets in C. elegans through cooperation with different THAP domain proteins, LIN-36 and LIN-15B, which use separate mechanisms.

Cell Reports · Oct 1, 2021Peer-reviewedGenomics