Klaus Elenius

The paper identifies a signaling axis involving SorLA, integrin, and HER2/HER3 that regulates apicobasal polarity in mucinous colorectal adenocarcinoma and shows its therapeutic relevance.

This study identifies recurrent ERBB4 mutations with oncogenic potential and resistance to targeted therapies, suggesting clinical implications for treatment strategies.

This study uses phosphoproteomic analysis in zebrafish to show that ErbB inhibitors affect multiple signaling pathways, leading to similar physiological phenotypes.

DMPA is a de novo multi-omics method that discovers signaling pathways and regulatory relationships across omics data, outperforming existing methods in low-sample and zero-inflated datasets.

DORM is a database of recurrent mutations in cancers, enabling search by protein, amino acid substitution, and regular expressions.