NeurosciencebioRxivPreprint
Aquaporin-4 mis-localization slows glymphatic clearance of α-synuclein and promotes α-synuclein pathology and aggregate propagation
Molly Braun, Matthew J. Simon, Jay Jang…·Jeffrey J. Iliff
This study shows that AQP4 mis-localization impairs glymphatic clearance of α-synuclein and promotes its aggregation and spread in neurodegenerative diseases.