Allison J. Schaser

This study shows that SCN2A deficiency in human brain assembloids disrupts cortico-striatal circuitry by impairing axonal projections and synaptic transmission, leading to hyperexcitability.

This study shows that alpha-synuclein overexpression alone does not cause vocalization deficits in mice, suggesting that aggregate pathology, not overexpression, is responsible for voice issues in Parkinson's disease.

This study analyzes brain lipid changes in aging mice using three mass spectrometry platforms, finding age-related increases in certain phospholipids and decreases in others.

This study shows that AQP4 mis-localization impairs glymphatic clearance of α-synuclein and promotes its aggregation and spread in neurodegenerative diseases.