Kevin M. Boergens

This study investigates structural changes in auditory nerve synapses after moderate noise exposure, finding increased presynaptic vesicle density without changes in synaptic contact area or release sites.

The paper introduces mito-SegEM, a method for efficiently mapping mitochondria in electron microscopy volumes using webKnossos, achieving accurate and efficient reconstruction across tissues.

The paper develops a pipeline to map every myelinated axon in non-human primate brains, enabling comprehensive analysis of long-distance neuronal connections.

This paper introduces photoemission electron microscopy (PEEM) as a new method for connectomics, offering synaptic resolution and faster imaging compared to traditional TEM and SEM.

The paper identifies a specialized disinhibitory network in cortical layer 4 driven by thalamic input, revealing subtype-specific connectivity patterns.

This paper describes a surgical technique using laser ablation to thin the pia mater in sheep, enabling safer insertion of high-density microelectrode arrays for neural recordings.

The paper introduces the Argo System, a high-density neural recording system with 65,536 channels, validated in rats and sheep for cortical recordings.

The paper examines the synaptic innervation patterns of apical tufts of cortical pyramidal cells in mice, revealing cell-type specific inhibitory input distributions.

The paper reports a dense connectomic reconstruction of mouse barrel cortex layer 4, revealing synaptic specificity and plasticity patterns in neuronal circuits.

FluoEM identifies multi-color fluorescent axons in 3D EM data without fiducial marks by matching neurite reconstructions from light microscopy.

SynEM automatically detects excitatory synapses in 3D electron microscopy images with high precision and recall, enabling large-scale connectomic analysis without manual annotation.