Author

Haoyu Wang

Shanghai Jiao Tong University

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Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Bioengineering· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:drug response / drug discovery· 3 Research Focus:gene regulatory network inference· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2

Frequent Co-Authors

Dongqing ZuoiD· 2 shared Haoran MuiD· 2 shared Jiakang SheniD· 2 shared Jing Xu· 2 shared Liu Yang· 2 shared Wei SuniD· 2 shared Xin HeiD· 2 shared Xiyu Yang· 2 shared

Activity by Year

2024-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Dongqing ZuoORCID

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Author profile →

7 papers

Recent·Most cited

Glutamine-regulated VCP acetylation creates a proteostasis vulnerability in RB1-deficient tumor

Bing‐Hui Yang, Ying Cao, Yining Tao, Haoyu Wang, Haoru Dong, Xiyu Yang, Xin He, Bowen Zhao, Kaiyuan Liu, Zongyi Wang, Jiakang Shen, Yan Yan, Qi Zhang, Zhuoying Wang, Yu Bing Lv, , Wei Sun

This study identifies VCP inhibition as a therapeutic strategy for RB1-deficient tumors by revealing glutamine-regulated VCP acetylation as a proteostasis vulnerability.

bioRxiv · Sep 17, 2026 · PreprintCell Biology

Comprehensive Complete-Genome Analysis of Lactobacillaceae and Bifidobacteriaceae Reveals Strain-Specific Metabolic Interactions in Chinese Gut Microbiota

Xin Tong, Hewei Liang, Yu Tian, Xinyu Yang, Ya Wang, Haoyu Wang, Yuzheng Gu, Zhihui Ma, Wenrui Su, Yanhong Liu, Sihang Cai, Zhiyin Lin, Peilin Zhang, Haifeng Zhang, Liang Xiao, , Yuanqiang Zou

The paper analyzes complete genomes of Lactobacillaceae and Bifidobacteriaceae strains to reveal strain-specific metabolic interactions in the Chinese gut microbiota.

bioRxiv · May 22, 2026 · PreprintMicrobiology

Nicotinamide-loaded Peptoid Nanotubes for Energy Regeneration in Acute Brain Injury

Hui Du, Thi Kim Hoang Trinh, Olivia C. Brandon, Renyu Zheng, Haoyu Wang, Kylie A. Corry, Thomas Ragnar Wood, Chun‐Long Chen, Elizabeth A. Nance

This study develops NAM-conjugated peptoid nanotubes to restore energy and reduce inflammation in acute brain injury models.

ACS Nano · Apr 13, 2026Peer-reviewedBioengineering

A distinct class of conjugative megaplasmids includes potential vehicles for prophage dissemination

Ling Yuan, Yiting Qin, Jacob West-Roberts, Karthik Anantharaman, Haoyu Wang, Yuanqiang Zou, Yi Duan, Antoni Pedro Camargo, Eugene V. Koonin, L. J. Chen

The paper identifies conjugative megaplasmids in the human gut microbiome that can disseminate prophage genomes across bacterial lineages, explaining their wide distribution.

bioRxiv · Feb 22, 2026 · PreprintMicrobiology

Genomic insights into post-domestication expansion and selection of body size in ponies

Xingzheng Li, Zihao Wang, Min Zhu, Binhu Wang, Shaohua Teng, Jing Yan, Haoyu Wang, Pengxiang Yuan, Shuwei Cao, Xiaolu Qu, Zhen Wang, Kai Zhan, Md. Panir Choudhury, Xintong Yang, Qi Bao, , Guoqiang Yi

The paper analyzes the genomic data of 385 horses from 49 breeds to explore the demographic history and genetic factors influencing body size in ponies, identifying cis-regulatory elements and genetic affinities.

Advanced Science · Feb 26, 2025Peer-reviewedGenomics

Efficient cell-wide mapping of mitochondria in electron microscopic volumes using webKnossos

Yi Jiang, Haoyu Wang, Kevin M. Boergens, Norman Rzepka, Fangfang Wang, Yunfeng Hua

The paper introduces mito-SegEM, a method for efficiently mapping mitochondria in electron microscopy volumes using webKnossos, achieving accurate and efficient reconstruction across tissues.

Cell Reports Methods · Feb 1, 2025Peer-reviewedCell Biology

A Self-Assembling Immune-Featured Osteosarcoma Patient/PDX Derived Organoid Model and Biobank for Personalized Immune Therapy

Haoran Mu, Yining Tao, Jinzeng Wang, Xin He, Qi Zhang, Weixi Chen, Bing Yao, Sen Ding, Xiyu Yang, Liyuan Zhang, Hongsheng Wang, Dongqing Zuo, Jiakang Shen, Mengxiong Sun, Haoyu Wang, , Yingqi Hua

The paper develops a patient/PDX-derived osteosarcoma organoid model and biobank to enable rapid testing of personalized immune therapies and drug development.

bioRxiv · Aug 11, 2024 · PreprintCancer Biology