Jingyu Zhao

This study shows that PINK1 loss causes age-dependent mitochondrial trafficking deficits in dopaminergic neurons via p38 MAPK hyperactivation, leading to impaired mitochondrial motility and increased oxidative stress.

This study investigates the neuroenergetics of dopamine release in mouse striatal regions, finding that the dorsal striatum relies more on oxidative phosphorylation while the nucleus accumbens shell relies more on glycolysis.