GeneticsbioRxivPreprint
A platform for the systematic interrogation of genetic interactions in human cells: 26 gene by genome-wide double knockout screens as a proof of concept
Andrew Chatr‐aryamontri, Li Zhang, Ndeye Khady Thiombane…·Thierry Bertomeu
The paper introduces a method for systematically studying genetic interactions in human cells using CRISPR/Cas9 screens and demonstrates its effectiveness through 26 gene by genome-wide knockout screens.
DOI 10.1101/2025.08.04.665369