James G. Patton

The paper shows that PTB depletion in zebrafish retina activates Muller glia proliferation and enhances regeneration through modulation of the senescence secretome.

The paper identifies a 31-factor regeneration-associated senescence signature by analyzing SASP factors in zebrafish retina regeneration across different injury models.

This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.

This study shows that 5-FU treatment alters the export and base modifications of small RNAs in extracellular vesicles from colorectal cancer cells.

The paper analyzes RNA-seq data from zebrafish to study miRNA arm switching during development, identifying patterns linked to gene regulation and isomiR roles in differential arm usage.