Kasey C. Vickers

N-aldehyde modified phosphatidylethanolamines formed by lipid peroxidation inhibit efferocytosis.

This study shows that N-aldehyde modified phosphatidylethanolamines (NAMPs) inhibit efferocytosis and are elevated under oxidative stress conditions.

Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis

The paper investigates how post-transcriptional modifications on tRNA fragments in HDL affect atherosclerosis by altering immune signaling and macrophage activation.

Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

5-Fluorouracil Treatment Represses Pseudouridine-Containing Small RNA Export into Extracellular Vesicles

This study shows that 5-FU treatment alters the export and base modifications of small RNAs in extracellular vesicles from colorectal cancer cells.

microRNA Expression Levels Change in Neonatal Patients During and After Exposure to Cardiopulmonary Bypass

The paper identifies miRNA expression changes in neonatal patients during and after cardiopulmonary bypass, linking them to inflammation and signal transduction pathways.

Physico-chemical principles of HDL-small RNA binding interactions.

The paper investigates how HDL binds to single-stranded small RNAs through interactions with apoA-I, revealing mechanisms that may enable extracellular RNA communication.

Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins

The paper introduces TIGER, a pipeline for analyzing extracellular small RNAs, demonstrating its ability to identify sRNAs on lipoproteins and in biofluids with high accuracy.