Author

Kyle T Vallone

Vanderbilt UniversityORCID 0000-0002-8322-9075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Gregory J. KonariD· 2 shared James G. PattoniD· 2 shared Tu Dac Nguyen· 2 shared Audrey L Lingan· 1 shared Billy G. HudsoniD· 1 shared Bradley P. ClarkeiD· 1 shared Carl E DarrisiD· 1 shared Gautam B. BhaveiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Gregory J. KonarORCID

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Author profile →

3 papers

Recent·Most cited

Collagen IV of basement membrane: V. Bromide-mediated sulfilimine bonds interlock the quaternary structure of NC1-hexamer of scaffolds enabling metazoan evolution.

Bradley P. Clarke, Vadim K. Pedchenko, Tetyana V. Pedchenko, Monica Moran, Jacob Edwards, Kyle T Vallone, Carl E Darris, Gautam B. Bhave, Patrick Page-McCaw, Julie K. Hudson, Sergei P. Boudko, Billy G. Hudson

The paper shows that sulfilimine bonds stabilize the quaternary structure of Col-IV121 hexamers across species and that bromide-mediated bond formation is evolutionarily conserved.

Journal of Biological Chemistry · Mar 6, 2026Peer-reviewedMolecular Biology

Depletion of Polypyrimidine tract binding protein 1 (ptbp1) activates Muller glia-derived proliferation during zebrafish retina regeneration via modulation of the senescence secretome

Gregory J. Konar, Audrey L Lingan, Kyle T Vallone, Tu Dac Nguyen, Zachary Flickinger, James G. Patton

The paper shows that PTB depletion in zebrafish retina activates Muller glia proliferation and enhances regeneration through modulation of the senescence secretome.

Experimental Eye Research · May 10, 2025Peer-reviewedCell Biology

Analysis of The Senescence Secretome During Zebrafish Retina Regeneration

Gregory J. Konar, Kyle T Vallone, Tu Dac Nguyen, James G. Patton

The paper identifies a 31-factor regeneration-associated senescence signature by analyzing SASP factors in zebrafish retina regeneration across different injury models.

Frontiers in Aging · Apr 16, 2025Peer-reviewedCell Biology