Divya Rajendran

Using Fiji as a simplified tool for assessing alveolar chord length and septal thickness in neonatal pulmonary disease research

The paper develops a Fiji plugin to measure alveolar chord length and septal thickness in BPD research, validated across animal models and human lungs.

Polyphosphate Discriminates Protein Conformational Ensembles More Efficiently than DNA Promoting Diverse Assembly and Maturation Behaviors

This study compares how polyphosphate and DNA influence the assembly of disordered proteins, showing polyP's superior ability to distinguish protein conformations and drive diverse assembly behaviors.

Robust statistical assessment of Oncogenotype to Organotropism translation in xenografted zebrafish

This paper develops an imaging-based assay using zebrafish larvae to assess organotropism of cancer xenografts and identifies EWSR1::FLI1 and SOX6 as plasticity factors enhancing metastatic adaptability.

Allosteric Modulation of MIF-2 Structure, Catalysis, and Biological Signaling via Cysteine Residues and a Small Molecule, Ebselen

This study investigates how Ebselen modulates MIF-2 structure, catalysis, and signaling through cysteine residues, revealing its impact on trimer stability and function.

Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma.

This study identifies Caveolin-1 as a context-dependent regulator of survival signaling in Ewing Sarcoma, revealing a reversible CD99High state with enhanced survival.

Adaptive Optics in an Oblique Plane Microscope

This paper demonstrates adaptive optics in an oblique plane microscope, improving resolution and signal strength in zebrafish embryos.

Anchorage-independent cell proliferation promoted by fascin's F-actin bundling

This study identifies fascin-1's role in promoting anchorage-independent proliferation through a novel signaling complex called PASS, which drives Rac1/PAK/JNK signaling in cancer cells.