BiochemistryJournal of Biological ChemistryPeer-reviewed
Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity
Maria Joao Almeida A Silva Pires, Seher Alam, Alen Lovrić…·Nicholas C.K. Valerie
This study uses CeTEAM biosensors to profile PARP inhibitor selectivity at the single-cell level, revealing PARP1 and PARP2 selectivity patterns and the role of HPF1 in drug binding.