NeurosciencebioRxivPreprint
HTT silencing delays onset and slows progression of Huntington disease like phenotype: Monitoring with a novel neurovascular biomarker
Hongshuai Liu, Chuangchuang Zhang, Jiadi Xu…·Wenzhen Duan
This study shows that HTT silencing in premanifest HD mice delays disease onset and slows progression, using CBVa as a noninvasive biomarker.