Author

Dominika Nąckiewicz

University of British ColumbiaORCID 0000-0001-5836-8789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. Bruce VerchereiD· 1 shared Derek L. Dai· 1 shared Galina SoukhatchevaiD· 1 shared Heather C. DenrocheiD· 1 shared Imelda W. Suen· 1 shared Jane VelgheiD· 1 shared Liam Stanley· 1 shared Mitsuhiro KombaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

C. Bruce VerchereORCID

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1 paper

Recent·Most cited

ImmunologyDiabetologiaPeer-reviewedDec 22, 2025

Islet amyloid disrupts MHC Class II antigen presentation and protects NOD mice from autoimmune diabetes.

Heather C. Denroche, Victoria Ng, Jane Velghe…·C. Bruce Verchere

This study shows that islet amyloid disrupts MHC Class II antigen presentation in islet macrophages, protecting NOD mice from autoimmune diabetes by reducing immune cell infiltration and antigen-specific T cell activation.

2 citations

mousescRNA-seq

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