Cell BiologybioRxivPreprint
Autophagy protects pancreatic β-cells during hypoxia and islet transplantation but is compromised by TFEB-lysosomal dysfunction
DOI 10.64898/2026.07.02.736213
Author
University of British ColumbiaORCID 0000-0001-7485-1746Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
Recent·Most cited
Heather C. Denroche, Victoria Ng, Jane Velghe…·C. Bruce Verchere
This study shows that islet amyloid disrupts MHC Class II antigen presentation in islet macrophages, protecting NOD mice from autoimmune diabetes by reducing immune cell infiltration and antigen-specific T cell activation.