Author

Rodrigo Galindo‐Murillo

Ionis Pharmaceuticals (United States)ORCID 0000-0001-5847-4143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Eric E. SwayzeiD· 2 shared Michael TanowitziD· 2 shared Stephanie K. KleiniD· 2 shared Thazha P. PrakashiD· 2 shared Alfred E. ChappelliD· 1 shared Andrew RodrigueziD· 1 shared Andrew T. Watt· 1 shared António Pinto‐DuarteiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Eric E. SwayzeORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 20, 2026

Delivery of small interfering RNA and antisense oligonucleotides across the blood-brain barrier with monovalent transferrin receptor 1 binding VHH-Fc fusion proteins

Ian J. Huggins, Michele Carrer, Jinro A. Santos…·Eric E. Swayze

This paper develops a VHH-Fc fusion protein to deliver siRNAs and ASOs across the BBB in rodents and NHPs, showing that binding affinity, DAR, and conjugation site affect delivery efficiency.

DOI 10.64898/2026.08.13.744307

mousenon-human primate

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Molecular BiologybioRxivPreprintJan 14, 2026

Tuning siRNA Specificity through Seed Region Incorporation of Deoxyribonucleotide Stereoisomers

Mehran Nikan, Thazha P. Prakash, Guillermo Vasquez…·Eric E. Swayze

This paper introduces modified nucleosides in siRNA seed regions to enhance specificity and reduce off-target effects while maintaining on-target activity.

DOI 10.64898/2026.01.13.699368

experimental assaydrug response / drug discovery

𝕏 PostBluesky