Peter Louis Carlen

This study compares neuronal development and function in bipolar disorder with and without familial mitochondrial disease using iPSC-derived neurons.

This study uses iPSC-derived cerebral organoids to show mitochondrial and inflammatory dysfunctions in bipolar disorder and tests potential therapeutic interventions.

The paper identifies wavelet phase coherence of ictal scalp EEG-extracted muscle activity as a potential biomarker for SUDEP, showing higher values in SUDEP patients.

This study shows that Panx1 channels in zebrafish have both anti- and pro-seizure effects through p2rx7 receptors and ATP signaling.

This study uses brain organoids to model WOREE, a severe epileptic encephalopathy, identifying CNS abnormalities and showing potential therapeutic rescue via WWOX expression.

The paper characterizes electrophysiological diversity among human cortical pyramidal neurons by analyzing sag currents and frequency preferences across different cortical layers.