Zilong Li

This paper presents the first whole-genome data for the giant forest hog, revealing its evolutionary relationship with warthogs and significant genetic differentiation between populations.

This study generates the first banteng reference genome and analyzes 78 resequenced samples to explore its domestication history and genetic structure.

The paper introduces an adjusted linkage disequilibrium measure that accounts for population structure, improving LD pruning and clumping in structured populations.

This study identifies 30 novel metabolite-gene associations in 34,394 Chinese pregnant women and finds pleiotropy and causal relationships between metabolites and diseases.

QUILT2 enables accurate genotype imputation from low coverage short and long reads and cell-free DNA, improving GWAS and PRS for maternal and fetal genomes.

vcfpp provides a fast and flexible C++ API for VCF/BCF file manipulation, with an R package showing competitive performance for variant analysis.

PCAone is a fast and memory-efficient PCA framework that outperforms existing methods on large-scale biobank and single-cell RNA sequencing data.

This study identifies cholesterol levels and WBC counts as causal factors for COVID-19 severity through GWAS and MR analysis, and highlights type I interferon pathways in disease mechanisms.

NGSremix estimates pairwise relatedness in admixed individuals from low-depth NGS data, outperforming existing methods by accounting for genotype uncertainty.