LeAnn J. Howe

The paper identifies dual regulation of DDI2/3 gene expression by Fzf1 and chromatin structure in yeast, showing Fzf1 acts as both activator and chromatin remodeler.

The paper shows MeCP2 binds to yeast promoters and inhibits transcription without DNA methylation or mammalian corepressors, and some Rett syndrome mutations reduce its toxicity.

This study shows that PAN2-PAN3 deadenylase activity is required for mitotic robustness under microtubule stress in yeast and human cells.

This study uses a fluorescent assay to show DNA replication can promote cryptic transcription in yeast when chromatin-stabilizing factors are absent.

This study shows that most histone acetylation depends on transcription, as inhibition of transcription reduces histone acetylation and affects HAT recruitment and activity.

This study shows FACT interacts with unstable nucleosomes in transcribed regions of S. cerevisiae, dependent on transcription by any RNA polymerase.

The paper shows that H3K4 and H3K36 methylation recruit the NuA3 complex to transcribed genes in S. cerevisiae, while acetylated H3K9 does not, and that the YEATS domain of Taf14 is not involved in recruitment.