Joshua A.R. Brown

The paper identifies dual regulation of DDI2/3 gene expression by Fzf1 and chromatin structure in yeast, showing Fzf1 acts as both activator and chromatin remodeler.

The paper shows MeCP2 binds to yeast promoters and inhibits transcription without DNA methylation or mammalian corepressors, and some Rett syndrome mutations reduce its toxicity.

This study shows that PAN2-PAN3 deadenylase activity is required for mitotic robustness under microtubule stress in yeast and human cells.

This study identifies Rtt107's role in preventing genome instability by interacting with Rad55 and Slx4, showing distinct functions in limiting crossover events and maintaining rDNA stability.