Author

Sebastian El Ghaity-Beckley

Tisch Cancer InstituteORCID 0000-0001-5878-0597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Bridget Kelly MarcellinoiD· 2 shared Agneesh BaruaiD· 1 shared Ahmed M. ElsaadiiD· 1 shared Alan H. ShihiD· 1 shared Andrew Paul Trotta· 1 shared Andriana G. KotiniiD· 1 shared Brianna Kelly· 1 shared Cara ClementelliiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Bridget Kelly MarcellinoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 20, 2026

TET2 and TP53 Mutations Cooperatively Modulate the Response to Inflammation to Promote Leukemic Transformation

Pablo Sánchez Vela, Brianna Kelly, Claudia Brady…·Alan H. Shih

This study shows that TET2 and TP53 mutations work together to promote leukemic transformation by altering inflammatory responses and chemotherapy tolerance in hematopoietic stem cells.

DOI 10.64898/2026.01.20.700390

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologyCell Communication and SignalingPeer-reviewedJan 25, 2025

Metabolic Adaptations To Acute Glucose Uptake Inhibition Converge Upon Mitochondrial Respiration For Leukemia Cell Survival

Monika Komza, Jesminara Khatun, Jesse D. Gelles…·Jerry E. Chipuk

This study shows that leukemia cells rely on increased mitochondrial respiration for survival when glucose uptake is acutely inhibited by KL-11743.

8 citations

humanmetabolomics

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