Shikha Sharan

This study identifies E-cadherin/YAP-dependent pyruvate carboxylase expression as a metabolic driver of breast cancer progression and metastasis, with therapeutic implications for epithelial TNBC.

This study uses imaging mass cytometry to analyze circulating tumor cells in mouse models, enabling the characterization of single cells and clusters in liquid biopsies.

This paper compares two 3D culture models for breast cancer cells, finding that the EmC model better mimics lung metastasis by altering metabolism and gene expression.