John F. Cryan

This study identifies CD11c+ microglia as a key driver of T cell dysfunction in diffuse midline glioma through genetic and orthotopic mouse models.

This study shows that disrupting the gut microbiota increases reward-seeking behavior in male mice and alters brain gene pathways and inflammation.

The paper investigates how early-life microbiota influences transcriptional and metabolic programs in the developing brainstem, identifying a critical window during which microbial colonization affects pathways linked to oligodendrocyte lineage progression and tumour biology.

The paper shows that reduced electron flux through complex IV leads to cytochrome c accumulation via increased stability and membrane retention, without increasing apoptosis sensitivity.

This study shows that cesarean section in mice alters brain barrier function, immune profiles, and metabolism in the neonatal brain, highlighting birth mode's impact on early brain development.

This study links the neuroactive potential of the elderly gut microbiome to mental health and cognition in older adults with cognitive complaints.

This study transfers exuberant toddler gut microbiota to rats, increasing their exploratory behavior without affecting locomotion or social behavior.

The paper creates saMBA, a large gut microbiome archive from South America, revealing high biodiversity and uniqueness, and highlights the need for more diverse microbiome research.

The paper shows that moderate exercise improves cognitive function and neurogenesis in mice, but these benefits disappear with higher intensity or duration, and that gut microbiota changes mediate these effects.

This study shows that germ-free mice have altered dendritic morphology in the nucleus accumbens, suggesting gut microbiota influences neuronal structure and may contribute to psychiatric disorders.

Kronos is an R-based tool for analyzing circadian rhythms in biological datasets, supporting complex study designs and high-dimensional omics data.