Benjamín Valderrama

Microbiota-sensitive glial and metabolic programs define a critical window in early postnatal brainstem development

The paper investigates how early-life microbiota influences transcriptional and metabolic programs in the developing brainstem, identifying a critical window during which microbial colonization affects pathways linked to oligodendrocyte lineage progression and tumour biology.

The Neuroactive Potential of the Elderly Human Gut Microbiome is Associated with Mental Health Status

This study links the neuroactive potential of the elderly gut microbiome to mental health and cognition in older adults with cognitive complaints.

Orchestrating Microbiome Analysis with Bioconductor

The paper introduces an open-source ecosystem for microbiome data science using Bioconductor, supporting modular workflows for analyzing complex, multi-modal datasets.

The South American MicroBiome Archive (saMBA): Enriching the healthy microbiome concept by evaluating uniqueness and biodiversity of neglected populations

The paper creates saMBA, a large gut microbiome archive from South America, revealing high biodiversity and uniqueness, and highlights the need for more diverse microbiome research.

Gut Microbiota Regulates Exercise-induced Hormetic Modulation of Cognitive Function

The paper shows that moderate exercise improves cognitive function and neurogenesis in mice, but these benefits disappear with higher intensity or duration, and that gut microbiota changes mediate these effects.