Author

Peilong Lu

Westlake UniversityORCID 0000-0001-5894-9268Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Aiqin Zhu· 1 shared Can Liao· 1 shared Chen Xiao ZhouiD· 1 shared Chia‐Heng HsiungiD· 1 shared David A. BakeriD· 1 shared Fan YangiD· 1 shared Huican Li· 1 shared Jan SteinkühleriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperSynthetic Biology

Aiqin Zhu

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Time-resolved fluorescent proteins towards fluorescence microscopy in the temporal and spectral domains

Zizhu Tan, Chia‐Heng Hsiung, Jiahui Feng, Yangye Zhang, Yihan Wan, Junlin Chen, Ke Sun, Peilong Lu, Jianyang Zang, Wen‐Xing Yang, Ya Gao, Jiabin Yin, Tong Zhu, Lu Yang, Zijian Pan, , Xin Zhang

This paper introduces time-resolved fluorescent proteins (TRFPs) that enable temporal-spectral resolved microscopy for multiplexed imaging and super-resolution in live cells.

Cell · Sep 22, 2025Peer-reviewedBiochemistry

Accurate de novo design of a voltage-gated anion channel

Chen Xiao Zhou, Huican Li, Jiaxing Wang, Zhilin Chu, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M. Gamal El-Din, Kun Wu, Peilong Lu

This paper designs a voltage-gated anion channel with voltage-dependent currents and chloride selectivity using de novo methods.

bioRxiv · Dec 25, 2024 · PreprintSynthetic Biology

Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes

Justin A. Peruzzi, Jan Steinkühler, Timothy Q. Vu, Taylor F. Gunnels, Vivian T. Hu, Peilong Lu, David A. Baker, Neha P. Kamat

This study investigates how hydrophobic mismatch affects membrane protein organization using protein design, simulations, and cell-free systems, showing deformation of membranes and controlled protein assembly.

Nature Communications · Apr 11, 2024Peer-reviewedSynthetic Biology