Justin A. Peruzzi

This study investigates how hydrophobic mismatch affects membrane protein organization using protein design, simulations, and cell-free systems, showing deformation of membranes and controlled protein assembly.

This study demonstrates how bacterial two-component systems can be used to enable transmembrane signaling in synthetic membranes, showing that performance can be tuned by altering membrane properties and protein engineering.

This paper improves cell-free expression of membrane proteins by identifying factors affecting synthesis and developing a model to optimize yield through membrane composition and N-terminal domain sequence adjustments.

The paper improves cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles in bacterial extracts to enhance membrane-bound functionality.

This paper demonstrates DNA-functionalized vesicles that enable targeted fusion and controlled protein expression in vitro.