Tamer M. Gamal El-Din

This paper designs Ca2+ channels with specific selectivity filter geometries using a bottom-up approach, showing higher Ca2+ conductance and structural accuracy.

This study investigates how equivalent gating-charge mutations in voltage-gated sodium channels lead to different functional outcomes through structural and electrophysiological analysis.

This paper designs a voltage-gated anion channel with voltage-dependent currents and chloride selectivity using de novo methods.