Thomas A. Zangle

This study shows that 3D spatiotemporal CNNs outperform 2D CNNs in classifying cell states from QPI timelapse data, with accuracy improving as more frames are added.

The paper uses quantitative phase imaging to measure B cell mass growth and finds an offset exponential model explains mass accumulation, indicating constant degradation during activation.

QUILPEN quantifies pigmentation and organelle content in melanocytes using label-free imaging, revealing heterogeneity and heritable pigment synthesis rates.

This paper demonstrates that multiparametric QPI can assess drug sensitivity in patient-derived breast cancer models, including cryopreserved samples, revealing cellular heterogeneity and resistance mechanisms.

This study compares the proliferative responses of marginal zone (MZ) and follicular (FO) B cells to TLR4 (LPS) and TLR9 (CpG) stimulation, revealing distinct growth, division, and death dynamics.

This study shows that dual FGFR/VEGFR inhibition causes regression of acral melanoma by targeting the tumor microenvironment rather than directly killing cancer cells.

This paper introduces a label-free imaging method called quadrant darkfield (QDF) to enhance subcellular structure analysis in living cells, showing improved resolution and consistency compared to traditional darkfield.

This paper introduces a platform combining quantitative phase imaging and microwell confinement to improve lineage tracking by measuring cell mass.