Robert L. Judson‐Torres

The paper investigates immune infiltration and triad formation in early melanoma progression using spatial transcriptomics, finding increased immune engagement in Stage I lesions compared to Stage 0.

This study identifies a kinase network and DAPK3-driven polarity complex that promotes HCC cell migration and metastasis using a multi-modal profiling approach.

This study shows that 3D spatiotemporal CNNs outperform 2D CNNs in classifying cell states from QPI timelapse data, with accuracy improving as more frames are added.

The paper identifies distinct melanocyte subpopulations in human skin based on mutation burden, showing LowMut cells are stem-like and spatially distinct from HighMut cells.

QUILPEN quantifies pigmentation and organelle content in melanocytes using label-free imaging, revealing heterogeneity and heritable pigment synthesis rates.

The paper identifies a novel interaction between BRAFV600E and TP53 in melanoma, suggesting that BRAFV600E inactivates TP53, explaining the rarity of TP53 alterations in this cancer type.

This study engineers CSPG4-targeting CAR-macrophages that inhibit melanoma growth in vitro and in vivo, showing promise for solid tumor immunotherapy.

This study shows that miR-290 and miR-302 clusters are essential for reprogramming fibroblasts to iPSCs, but individually are not required, while their combined loss blocks the process.

This study shows that dual FGFR/VEGFR inhibition causes regression of acral melanoma by targeting the tumor microenvironment rather than directly killing cancer cells.

This paper introduces a label-free imaging method called quadrant darkfield (QDF) to enhance subcellular structure analysis in living cells, showing improved resolution and consistency compared to traditional darkfield.

This study develops UCL-211, a transdermal delivery system for miR211-5p, which stabilizes BRAFV600E+ melanocytic nevi by maintaining them in a growth-arrested state.

This study analyzes acral melanoma genomes and transcriptomes from Mexican patients, finding ancestry-related mutation patterns and survival differences.

This study genotypes individual melanocytes from human skin, revealing mutation patterns linked to sun exposure, skin cancer risk, and melanoma origins.