R. L. Belote

QUILPEN quantifies pigmentation and organelle content in melanocytes using label-free imaging, revealing heterogeneity and heritable pigment synthesis rates.

This study engineers CSPG4-targeting CAR-macrophages that inhibit melanoma growth in vitro and in vivo, showing promise for solid tumor immunotherapy.

This study shows that dual FGFR/VEGFR inhibition causes regression of acral melanoma by targeting the tumor microenvironment rather than directly killing cancer cells.

This paper introduces a label-free imaging method called quadrant darkfield (QDF) to enhance subcellular structure analysis in living cells, showing improved resolution and consistency compared to traditional darkfield.

This study analyzes acral melanoma genomes and transcriptomes from Mexican patients, finding ancestry-related mutation patterns and survival differences.

This study genotypes individual melanocytes from human skin, revealing mutation patterns linked to sun exposure, skin cancer risk, and melanoma origins.