Author

Giovannino Silvestri

University of Maryland, BaltimoreORCID 0000-0001-5911-6997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aditi ChatterjeeiD· 2 shared Maria R. BaeriD· 2 shared Blair P. Rendina· 1 shared Catherine Choy SmithiD· 1 shared Chozha Vendan RathinamiD· 1 shared Christopher M. BaileyiD· 1 shared Donald Small· 1 shared Eli E. BariD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

Aditi ChatterjeeORCID

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3 papers

Recent·Most cited

Cancer BiologyLeukemiaPeer-reviewedJun 2, 2026

Sphingosine-1-phosphate receptor modulators resensitize FLT3-ITD acute myeloid leukemia cells with NRAS mutations to FLT3 inhibitors

Aditi Chatterjee, Moaath K. Mustafa Ali, Christopher M. Bailey…·Maria R. Baer

This study shows that S1P receptor modulators resensitize NRAS-mutated FLT3-ITD AML cells to FLT3 inhibitors by inhibiting downstream signaling pathways.

2 citationstop 4%

humanproteomics

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Cancer BiologybioRxivPreprintMay 15, 2026

Glutamine-dependent downregulation of FLT3-ITD is a mechanism of FLT3 inhibitor resistance in FLT3-ITD AML in hypoxia

Giovannino Silvestri, Aditi Chatterjee, Blair P. Rendina…·Maria R. Baer

The paper investigates how hypoxia and glutamine affect FLT3 inhibitor resistance in FLT3-ITD AML, finding that glutamine reduces FLT3-ITD expression.

DOI 10.64898/2026.05.02.722336

humanbulk RNA-seq

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ImmunologybioRxivPreprintApr 22, 2025

Influenza virus infection in the lungs leads to pancytopenia and defective immune cell differentiation program in the thymus and bone marrow

Prajakta Shinde, Giovannino Silvestri, Panjamurthy Kuppusamy…·Chozha Vendan Rathinam

This study shows that influenza virus infection causes reduced immune cell counts and impaired differentiation in the thymus and bone marrow, linked to systemic inflammation and oxidative stress.

DOI 10.1101/2025.04.22.650071

mouseflow cytometry

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