Guanghui Li

Spatial and network principles behind neural generation of locomotion

The paper proposes spatial and network principles for locomotion generation in the spinal cord using a mouse model and integrates single-cell RNA sequencing with spatial transcriptomics.

Multimodal layer-crossing interrogation of brain circuits enabled by microfluidic axialtrodes

This paper introduces a microfluidic axialtrode for multimodal neural interfacing, enabling spatially distributed optogenetics, electrophysiological recording, and drug delivery across brain layers.

Neural manifolds that orchestrate walking and stopping

The paper investigates neural dynamics underlying walking and stopping in rats, finding locomotion follows a limit-cycle attractor and stopping transitions to a fixed-point attractor.

In vivo evaluation of thermally drawn biodegradable optical fibers as brain neural interfaces

This study evaluates biodegradable PDLLA optical fibers as neural interfaces in mice, showing degradation and efficient SW-NIR light transmission with potential for optogenetics and therapy.