Neela Krushna Codadu

This study shows that focal loss of astrocytic Kir4.1 in the adult hippocampus causes seizures, spreading depolarizations, and postictal impairments.

This paper presents a bidirectional neural interface combining graphene technologies for recording and stimulation, showing that recording performance is not compromised during stimulation.

This paper introduces a microfluidic axialtrode for multimodal neural interfacing, enabling spatially distributed optogenetics, electrophysiological recording, and drug delivery across brain layers.

This study shows that reduced GluN2A expression in rat models decreases seizure-like activity in specific in vitro epilepsy models.

The paper uses RNA sequencing to analyze transcriptomic changes in mouse neocortical tissue exposed to epileptiform activity, identifying gene expression alterations linked to epilepsy.

The paper introduces a GUI toolkit for analyzing LFP data from HD-MEA recordings, demonstrating its utility in detecting seizure propagation in Scn1aHet mice.

The paper compares two in vitro models of epileptic seizures, finding differences in glutamatergic involvement and seizure-like event characteristics.

The paper investigates the cellular mechanisms of benzodiazepine resistance in status epilepticus, finding that persistent high intraneuronal chloride levels contribute to reduced GABAA receptor function and enhanced epileptiform activity.

The paper shows that epileptiform activity transitions in vitro arise from shifts in ictal sources, with hippocampal activity entraining other cortical areas through non-synaptic mechanisms.