Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1
Margot Van Nerom, Junaid Ahmed, Tamás Lázár…·Péter Tompa
This study shows that C9orf72-derived arginine-rich dipeptide repeats enhance G3BP1 phase separation, contributing to ALS and FTD pathology.
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