Author

Christian M.A.H. Freund

Leiden University Medical CenterORCID 0000-0001-5940-397XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Albert Blanch-AsensioiD· 1 shared Babet van der VaartiD· 1 shared Christine L. MummeryiD· 1 shared James GallantiD· 1 shared Richard P. DavisiD· 1 shared Sebastiaan J. van KampeniD· 1 shared Valeria V. OrlovaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Albert Blanch-AsensioORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintAug 22, 2025

Controlled Induction of ALK1 in ACVRL1-null hiPSC-derived Endothelial Cells Provides Insight into Organ-Restricted AVMs in HHT

Sebastiaan J. van Kampen, Albert Blanch-Asensio, James Gallant…·Valeria V. Orlova

The paper develops a tunable in vitro model to study ALK1's role in HHT by inducing ALK1 in ACVRL1-null hiPSC-derived endothelial cells, showing threshold-dependent restoration of endothelial function.

1 citation

humanbulk RNA-seq

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