Bradford J. Smith

This study shows that Siglec-F protects against elastase-induced lung inflammation and emphysema by regulating airspace macrophages in mice.

This study shows that Siglec-F deficiency reduces fibrosis in bleomycin-induced lung injury by altering gene expression in airspace macrophages.

This study uses an agent-based model to simulate fibrotic development in the lung, finding that lung architecture enhances tissue deposition in fibrosis.

This paper develops a hypothesis-driven model of the human lung-ventilator system to improve parameter estimation and characterization of ventilatory patterns in ARDS.