Nayim González-Rodríguez

The paper identifies RUVBL1/2-RPAP3 interface as a vulnerability and develops de novo protein binders that selectively disrupt R2TP, reducing PIKK levels without affecting other RUVBL1/2 complexes.

This paper designs sequence-specific DNA binding proteins using deep learning, achieving a 100-fold improvement in success rates over previous methods.

This paper introduces BinderFlow, a modular pipeline for protein binder design, and BFmonitor, a dashboard for campaign monitoring, making generative protein design more accessible.

This study determines the structure of the complete extracellular bacterial flagellum, revealing mechanisms of flagellin incorporation and filament assembly.

The paper identifies structural interactions between yeast CST and Pol/primase complexes that are essential for telomere maintenance and protection, showing their joint role in telomere regulation.