Author
Spanish National Cancer Research CentreORCID 0009-0000-8390-3608Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Nayim González-Rodríguez, Andrés López‐Perrote, Clara Reglero…·Rafael Fernández-Leiro
The paper identifies RUVBL1/2-RPAP3 interface as a vulnerability and develops de novo protein binders that selectively disrupt R2TP, reducing PIKK levels without affecting other RUVBL1/2 complexes.
Samuel Miguez-Amil, A. Grande-García, Ismael Plaza-G.A.…·Rafael Fernández-Leiro
This study identifies a Template Stabilising Motif in human Polγ that enables DNA synthesis through replication roadblocks by stabilizing template engagement.
Carlos Chacón-Sánchez, Nayim González-Rodríguez, Óscar Llorca, Rafael Fernández-Leiro
This paper introduces BinderFlow, a modular pipeline for protein binder design, and BFmonitor, a dashboard for campaign monitoring, making generative protein design more accessible.