Pablo Reina-Gonzalez

This study shows that prolonged low-dose inhalation of paraquat in mice causes male-specific dopaminergic neuron loss and motor deficits, linking it to Parkinson's disease.

This study compares proteomic and metabolomic changes in genetic and environmental Parkinson's disease models, identifying purine metabolism as a shared pathway involved in neurotoxicity.

This study identifies biotin pathway dysregulation as a key mechanism linking manganese toxicity to Parkinson's disease using Drosophila and human iPSC models, showing biotin supplementation rescues neurotoxic phenotypes.