Pharmacology & ToxicologybioRxivPreprint
Direct β1/β2 AMPK activation reduces liver steatosis but not fibrosis in a mouse model of non-alcoholic steatohepatitis
KARLY M. MATHER, Michelle L. Boland, E. L. Rivers…·David M. Smith
This study evaluates BI9774, an AMPK activator, in a mouse model of NASH, finding it reduces liver steatosis but not fibrosis and causes cardiac side effects.
5 citations