Author

Clayton Hull-Crew

University of Colorado Colorado SpringsORCID 0000-0001-5984-2972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:fungi (other)· 3 Assay:DNA methylation· 1 Assay:Hi-C· 1

Frequent Co-Authors

Andrew D. KlockoiD· 3 shared Ashley W. ScaddeniD· 2 shared Abigail M. DeaveniD· 1 shared Aileen R. FerraroiD· 1 shared Alayne S. GraybilliD· 1 shared Cynthia A Vino· 1 shared Farh KaddariD· 1 shared Felicia Ebot-OjongiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersGenetics

Andrew D. KlockoORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 3, 2026

Centromeres are hotspots of cytosine methylation epimutations in a filamentous fungus

Mariana Villalba de la Peña, Clayton Hull-Crew, Taylor R Hutter…·Ilkka Kronholm

The paper identifies centromeres as hotspots for spontaneous DNA methylation epimutations in Neurospora crassa, showing these changes are mitotically stable and occur much more frequently than genetic mutations.

1 citation

fungi (other)DNA methylation

𝕏 PostBluesky

GeneticsProceedings of the National Academy of SciencesPeer-reviewedSep 29, 2025

Histone deacetylase-1 is required for epigenome stability in Neurospora crassa

Felicia Ebot-Ojong, Aileen R. Ferraro, Rochelle E. Yap…·Zachary Lewis

This study identifies HDA-1 as essential for maintaining epigenome stability in Neurospora crassa by regulating H3K27me3 and heterochromatin integrity.

5 citations

fungi (other)experimental assay

𝕏 PostBluesky

GenomicsProceedings of the National Academy of SciencesPeer-reviewedNov 14, 2023

Histone deacetylation and cytosine methylation compartmentalize heterochromatic regions in the genome organization of Neurospora crassa

Ashley W. Scadden, Alayne S. Graybill, Clayton Hull-Crew…·Andrew D. Klocko

This study investigates how the HCHC complex affects genome organization in Neurospora crassa by altering histone acetylation and cytosine methylation, leading to changes in heterochromatic region compaction and interactions.

7 citations

fungi (other)Hi-C

𝕏 PostBluesky