Ilkka Kronholm

This paper shows that the fungal ATRX ortholog SAD-6 uses a unique histone H4 variant for genome surveillance and defense, revealing its role in various genomic regions and a repeat-induced point mutation pathway.

The paper identifies centromeres as hotspots for spontaneous DNA methylation epimutations in Neurospora crassa, showing these changes are mitotically stable and occur much more frequently than genetic mutations.

This study examines how population size affects adaptation to fluctuating temperatures in fission yeast, finding no significant impact on adaptation or trade-offs.

This study uses genome-wide association mapping to investigate thermal adaptation in Neurospora crassa, finding polygenic thermal tolerance with no significant trade-offs between fluctuating and constant temperatures.

This study identifies loci influencing thermal performance curves in Neurospora crassa and finds weak evidence of trade-offs between alleles at different temperatures.

The paper investigates how chromatin structure affects mutation rates and spectra in Neurospora crassa, finding higher mutation rates in specific chromatin domains.

The paper constructs marked Neurospora crassa strains and develops a Bayesian method to estimate fitness in competition experiments, showing fitness differences related to mating type and a qde-2 mutation.

The paper examines how acclimation time and epigenetic mechanisms affect Neurospora crassa growth in fluctuating temperatures, finding that acclimation time improves predictions but epigenetic effects are limited.

This study investigates how epigenetic mechanisms influence phenotypic plasticity in Neurospora crassa across different environments, showing context-dependent effects of histone methylation and RNA interference.