Author

Matthijs Raaben

The Netherlands Cancer InstituteORCID 0000-0001-5989-289XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Thijn R. BrummelkampiD· 2 shared Abdelghani MazouziiD· 1 shared Arthur P.H. de JongiD· 1 shared Chantal Vaarting· 1 shared Empar Baltasar PéreziD· 1 shared Guido Hartmann· 1 shared Hisham N. AlsohybeiD· 1 shared Isabelle V. Peña· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Thijn R. BrummelkampORCID

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2 papers

Recent·Most cited

Cell BiologyNaturePeer-reviewedMay 7, 2025

PLA2G15 is a Lysosomal BMP Hydrolase and Its Targeting Ameliorates Lysosomal Disease

Kwamina Nyame, Jian Xiong, Hisham N. Alsohybe…·Monther Abu-Remaileh

This study identifies PLA2G15 as a lysosomal BMP hydrolase and shows its targeting improves lysosomal disease symptoms in NPC1 models.

49 citationstop 1%

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Cell BiologybioRxivPreprintJan 12, 2025

Identification of critical factors of the replication stress response in human cells

Louise M.E. Janssen, Empar Baltasar Pérez, Chantal Vaarting…·Jonne A. Raaijmakers

The paper identifies genes critical for the replication stress response in human cells, revealing both known and novel factors that protect against replication stress-induced toxicity.

1 citation

humangenetic perturbation / CRISPR

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