Lauren E. Byrnes

The paper identifies MYCL and HEY1 as opposing transcription factors mediating Notch-dependent airway stem cell fate decisions through single-cell RNA sequencing and CUT&RUN.

The paper constructs a single-cell RNA-seq atlas of the adult Drosophila ovary and identifies a new form of cellular plasticity in response to starvation.

This study maps mouse and human cochlea development using single-cell RNA-sequencing and a new clustering algorithm, identifying new cell types and gene associations related to hearing loss.

The paper introduces demuxlet, an algorithm that uses natural genetic variation to multiplex single-cell RNA-seq samples, enabling accurate sample identification and doublet detection in pooled experiments.