Author

Shuvra Shekhar Roy

Institute of Genomics and Integrative BiologyORCID 0000-0001-6005-2767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Mercy RophinaiD· 2 shared Paras SehgaliD· 2 shared Shantanu ChowdhuryiD· 2 shared Sridhar SivasubbuiD· 2 shared Vinod ScariaiD· 2 shared Abhinav K. JainiD· 1 shared Amit AwasthiiD· 1 shared Ananya NandyiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Mercy RophinaORCID

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3 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedAug 19, 2024

Artificially inserted G-quadruplex DNA secondary structures induce long-distance chromatin activation

Shuvra Shekhar Roy, Sulochana Bagri, Soujanya Vinayagamurthy…·Shantanu Chowdhury

The paper inserts G-quadruplex DNA sequences into cells and shows they increase chromatin looping and gene activation over long distances.

7 citations

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Molecular BiologybioRxivPreprintMay 31, 2022

Anti-COVID-19 Activity of FDA Approved Drugs through RNA G-quadruplex Binding

Shuvra Shekhar Roy, Shalu Sharma, Zaigham Abbas Rizvi…·Shantanu Chowdhury

This study identifies FDA-approved drugs that bind G-quadruplexes in SARS-CoV-2 genomes, showing significant inhibition of viral replication in hamsters and cell cultures comparable to Remdesivir.

1 citation

mousebulk RNA-seq

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GenomicsPLoS ONEPeer-reviewedFeb 17, 2021

High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next generation sequencing

Rahul C. Bhoyar, Abhinav K. Jain, Paras Sehgal…·Sridhar Sivasubbu

This study evaluates the COVIDSeq protocol for SARS-CoV-2 detection and genetic epidemiology, showing high concordance with RT-PCR and identifying novel variants and lineages.

146 citationstop 1%

whole-genome sequencingexperimental assay

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