Rahul C. Bhoyar

This study evaluates a full-length 16S rRNA sequencing framework for species-resolved human gut microbiome profiling, showing improved taxonomic resolution compared to short-read methods.

This study identifies TAAL, a lncRNA that modulates Tie1 signaling and vascular function in diabetic retinopathy, showing its role in endothelial cell behavior and potential therapeutic relevance.

This paper introduces SNAPseq, a high-throughput NGS method for detecting β-thalassemia and sickle cell disease with 100% sensitivity and specificity using noninvasive samples.

This study analyzes whole genome sequences of 1029 Indian individuals to characterize blood group antigens and alleles, identifying rare phenotypes and comparing them with global populations.

The paper reports genome sequences of Lumpy Skin Disease Virus from an outbreak in India, finding a distinct lineage with significant genetic variations compared to the reference genome.

This study reports HNA allele and genotype frequencies in the Indian population using whole genome sequencing, finding significant differences in HNA5 variant prevalence compared to other global populations.

The paper analyzes genetic variants of human platelet antigens in 1029 Indian genomes to determine allele frequencies and compare them to global populations.

This study analyzes Indian genetic variations in the kinome to identify sequence, structural, and pharmacogenomic differences compared to global datasets, highlighting implications for drug safety and adverse reactions.

The paper analyzes intra-host Single Nucleotide Variations (iSNVs) in SARS-CoV-2 genomes across multiple time points and regions, finding that many iSNVs later become population-level variants and some may contribute to immune escape.

The paper identifies a novel 5,296 bp deletion in the BTK gene in an Indian family with X-linked agammaglobulinemia through whole genome sequencing and carrier screening.

FELUDA uses FnCas9 for rapid, accurate nucleobase detection and is implemented in a point-of-care diagnostic tool for SARS-CoV-2.

The paper analyzes SARS-CoV-2 isolates from Kerala, India, identifying 166 unique variants, including 4 novel ones, and reports on their genetic epidemiology and potential impact on diagnostics.

This study evaluates the COVIDSeq protocol for SARS-CoV-2 detection and genetic epidemiology, showing high concordance with RT-PCR and identifying novel variants and lineages.

This study sequenced SARS-CoV-2 genomes from Andhra Pradesh, identifying 564 variants including 15 novel ones and 4 associated with increased infectivity.

The paper investigates the genetic epidemiology of immune escape variants in SARS-CoV-2 genomes globally.